Sure. The things you can do with your disability may be limited, but that doesn't mean your quality of life has to be. It's all about how you decide to deal with it. you can go with the "Oh poor me," approach. But with that approach, I guarantee that your quality of life will be poor. But, if you take the approach of just accepting your physicality as something you just can't change, and decide that you are going to make the best of it, then your quality of life can improve greatly. There are so many things you can do to enjoy life, even if mobility is an issue.
I am disabled, though I am luckily not in a wheelchair just yet. I do my best to live my life and not let my disabilities control it. I still enjoy doing things I am capable of. Right now, I am learning leather crafting and am enjoying that. Once I learn it, I am planning on making videos on Youtube, showing how to do it. Anyone can make videos for you tube in any area they know about. I's really simple. All you need is a camera (cell phone cams work perfectly), a table if there's something you need to show people, or even just your own voice to explain the topic on which you are instructing. You can also do product reviews.
My son loves reviewing products on you tube. There are also many other hobbies you can practice to keep yourself inspired and entertained. For example, you could get clock kits and make clocks. The kits go from very simple to really complex. You could start with simple ones and work your way up if you enjoy it. There are endless hobbies you can get yourself into. It would be impossible to list them all, but you can surely find something you are interested in.
I realize that everyone's disabilities are different and the ideas I have mentioned may not work for everyone/ But I am sure you can find something that you enjoy. Take it from me. Life is better if you find and pursue what you love and stop feeling sorry for yourself. Go ahead. Live your life to the best of your ability.